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Study identifier: NCT06906562 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

Condition: Advanced Pancreatic Carcinoma · Metastatic Pancreatic Carcinoma · Stage II Pancreatic Cancer AJCC v8  ·  Sponsor: Sameek Roychowdhury

PhasePhase 2
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) or has spread from where it first started to other places in the body (metastatic) and that have abnormal changes (alterations) in the fibroblast growth factor receptor (FGFR) gene. FGFR genes are genes that, when altered, can lead to and promote the growth of cancer in patients. Researchers want to test if using pemigatinib can block the function of these abnormal FGFR genes and prevent the tumor from growing and whether treatment can help improve overall quality of life.

This description comes directly from the study's public registry record.

Talk to the study team

Sameek Roychowdhury, MD, PhD  ·  734-474-8359  ·  sameek.roychowdhury@osumc.edu

The Ohio State University Comprehensive Cancer Center and James Cancer Hospital  ·  OSUCCCClinicaltrials@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (109)

Ohio State University-TelemedicineBirmingham, Alabama, United StatesRecruiting
Ohio State University-TelemedicineMobile, Alabama, United StatesRecruiting
Ohio State University TelemedicineMontgomery, Alabama, United StatesRecruiting
Ohio State University-TelemedicineAnchorage, Alaska, United StatesRecruiting
Ohio State University TelemedicineFlagstaff, Arizona, United StatesRecruiting
Ohio State University-TelemedicinePhoenix, Arizona, United StatesRecruiting
Ohio State University-TelemedicineTucson, Arizona, United StatesRecruiting
Ohio State University-TelemedicineHot Springs, Arkansas, United StatesRecruiting
Ohio State University TelemedicineFresno, California, United StatesRecruiting
Ohio State University-TelemedicineLos Angeles, California, United StatesRecruiting
Ohio State University-TelemedicineSan Diego, California, United StatesRecruiting
Ohio State University-TelemedicineSan Francisco, California, United StatesRecruiting

+ 97 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06906562