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Study identifier: NCT06906237 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Scarless Advanced Breast Extended Oncoplasty: The ScarABEO Study

Condition: Breast Cancer · Oncoplastic Breast Surgery · Oncoplastic Breast-conserving Surgery  ·  Sponsor: Istituto Oncologico Veneto IRCCS

PhaseN/A
Planned participants250
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Breast conserving surgery followed by radiotherapy is the gold standard treatment for early breast cancer. Cases with unfavorable tumor volume to breast volume ratio or challenging localizations are at higher risk of margin infiltration or poor aesthetic outcomes. While margin infiltration represents one of the strongest predictors of local recurrence, unappealing cosmetic results may significantly impair survivors' quality of life. Over the past two decades, the adoption of oncoplastic breast conserving surgery (OBCS) techniques has shown promise in improving both oncological and aesthetic outcomes after breast cancer surgery. Partial breast volume reconstruction (PBR) after OBCS is obtained through volume displacement (which involves remodelling and redistributing glandular tissue) and volume replacement (when the volume used to reconstruct the defect comes from an extramammary site) techniques. One of the greatest examples of volume replacement techniques in breast surgery involves the use of chest wall perforator flaps (CWPF). The use of these well-vascularized dermo-adipose flaps offers oncologically safe wide resection while obtaining excellent cosmetic outcomes. It is particularly suitable for patients with non-ptotic small to medium-sized breasts and cases with an unfavorable tumor volume to breast volume ratio. CWPFs can decrease mastectomy rates in breast cancer surgery, thus avoiding the disadvantages associated with implant-based reconstruction. Consequently, the…

This description comes directly from the study's public registry record.

Talk to the study team

Massimo Ferrucci  ·  +39 3331779209  ·  massimoferrucci@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Veneto Institute of OncologyPadova, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06906237