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Study identifier: NCT06905561 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Topical Diclofenac for Prevention of Radiation-induced Dermatitis

Condition: Head and Neck Tumor · Breast Cancer  ·  Sponsor: The Second Affiliated Hospital of Hainan Medical University

PhaseNA
Planned participants156
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Radiation induced dermatitis (RID) is one of the leading adverse events of radiation therapy, and if occurred could alter the course of therapy. The main pathways of RID is inflammation and oxidative stress on local and systemic bases. The Diclofenac is a COX-2 inhibitor and Nonsteroidal anti-inflammatory drugs whose anti-inflammatory and antioxidant activities have been proven in several clinical trials. Thus, the aim of the present study is to evaluate the efficacy of Diclofenac sodium gel as a prophylactic method against the development of RID.

This description comes directly from the study's public registry record.

Talk to the study team

yuecan zeng  ·  19946610752  ·  wellyy2005@hainmc.edu.cn

junnv xu  ·  18208946196  ·  xujunnv@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Affiliated Hospital of Hainan Medical UniversityHaikou, Hainan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06905561