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Study identifier: NCT06904729 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Chimeric Antigen Receptors T Cells for Refractory/Recurrent Lupus Nephritis in Children

Condition: Lupus Nephritis  ·  Sponsor: Guangzhou Women and Children's Medical Center

PhasePhase 3
Planned participants50
Who can joinAll sexes, 6 Years to 18 Years
Healthy volunteersNo

About this study

The goal of this prospective, open, single-arm clinical trial was to evaluate the safety and potential efficacy of CAR T cell therapy in children with refractory/recurrent lupus nephritis. The persistence and cell phenotype of CAR-T cells in vivo and CAR-T treatment-related inflammatory factors were evaluated after treatment. To explore new therapeutic methods, in order to reduce the side effects of traditional therapeutic drugs, increase curative effect, and finally make patients obtain long-term survival and improve survival quality.

This description comes directly from the study's public registry record.

Talk to the study team

Xia Gao, M.D.  ·  86+020-81330569  ·  gaoxiagz@vip.163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Guangzhou Women and Children Medical CenterGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06904729