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Study identifier: NCT06904326 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

CLUBE (UBE Stability / Dynamic Radio)

Condition: Spinal Instability  ·  Sponsor: Clinique Saint Jean, France

PhaseNA
Planned participants400
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

Degenerative pathologies of the spine affect a large proportion of the increasingly ageing population, and are a major public health issue. When conservative treatments (physiotherapy, analgesics, infiltrations) fail, surgical treatment is preferred. Traditionally, a simple lumbar recalibration operation is preferred (bilateral laminectomy decompression), but this may affect spinal stability. In cases of spondylolisthesis or preoperative instability, lumbar fusion (arthrodesis) is sometimes necessary to avoid the risk of major instability, but such an operation is not without risk and may require repeat surgery. The development of new surgical techniques such as uni or bilateral laminotomies, which are less radical, has made it possible to avoid some arthrodeses. Nowadays, the emergence of new surgical techniques such as endoscopy has further reduced the risk of destabilization (shorter post-operative convalescence, less atrophy of the paraspinal muscles) and improved surgeon comfort (better vision and easier instrument handling). Unilateral biportal endoscopy (UBE) is one of two endoscopic techniques and has proven its effectiveness for lumbar decompression in terms of clinical benefits. However, there is no scientific evidence on spinal stability after recalibration under UBE. We believe that minimizing invasiveness with UBE during simple lumbar recalibration surgery can preserve spinal stability, thereby reducing the need for lumbar fixation and lowering the cost of ca…

This description comes directly from the study's public registry record.

Talk to the study team

Guillaume Lonjon, Dr  ·  (0)467413453  ·  guilonjon@gmail.com

Marion MAYNADIER  ·  (0)467413453  ·  marionmaynadier.recherche@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Clinique St Jean Sud de FranceMontpellier, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT06904326