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Study identifier: NCT06904183 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Lenvatinib, Sintilimab, and DEB-TACE With/Without HAIC for HCC >7 cm With PVTT

Condition: Hepatocellular Carcinoma Non-resectable  ·  Sponsor: Second Affiliated Hospital of Guangzhou Medical University

PhasePhase 2
Planned participants320
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study is conducted to evaluate the efficacy and safety of lenvatinib plus sintilimab, transarterial chemoembolization (TACE) with drug-eluting beads (DEB-TACE) and hepatic artery infusion chemotherapy (HAIC) with FOLFOX regemen (LEN+SIN+DEB-TACE+HAIC) versus lenvatinib plus sintilimab and DEB-TACE (LEN+SIN+DEB-TACE) for large hepatocellular carcinoma (\> 7cm) with portal vein tumor thrombosis (PVTT).

This description comes directly from the study's public registry record.

Talk to the study team

Mingyue Cai, Dr.  ·  +86-20-34156205  ·  cai020@yeah.net

Kangshun Zhu, Dr.  ·  +86-20-34156205  ·  zhksh010@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06904183