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Study identifier: NCT06904027 Synced from ClinicalTrials.gov · July 28, 2026
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A Clinical Study of Glycerol Phenylbutyrate in Chinese Patients With Urea Cycle Disorders

Condition: Urea Cycle Disorders  ·  Sponsor: Tongji Hospital

PhaseN/A
Planned participants40
Who can joinAll sexes, 0 Years to 18 Years
Healthy volunteersNo

About this study

Urea cycle disorders (UCD) are rare diseases in China, would lead to high mortality and disability, which require long-term management due to the recurrent symptoms. This multi-center, prospective, single-arm study was designed to assess the efficacy and safety of Glycerol Phenylbutyrate for Chinese pediatric patients with UCD, to provide the additional references and treatment options for Chinese UCD patients, and enhance the clinical management of UCD in China. This study primarily observes patients with UCD who are on long-term treatment with glyceryl phenylbutyrate, the total planned observation period is 5 years.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaoping Luo, M.D.  ·  027-83662640  ·  xpluo@tjh.tjmu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (5)

Peking University First HospitalBeijing, Beijing Municipality, ChinaRecruiting
Guangzhou Women and Children's Medical CenterGuangzhou, Guangdong, ChinaRecruiting
Tongji HosipitalWuhan, Hubei, ChinaRecruiting
Xinhua Hospital, Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting
Children's Hospital of Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06904027