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Study identifier: NCT06903923 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Bone Metabolism in 12-21 Year Olds Undergoing Glucagon Like Peptide (GLP)-1 Receptor Agonist Therapy

Condition: Obesity in Children · Bone Strength · GLP - 1  ·  Sponsor: University of Virginia

PhasePhase 2
Planned participants120
Who can joinAll sexes, 12 Years to 21 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to compare bone health markers over 24 months in participants 12 - 21 years of age with obesity who are starting the glucagon-like peptide-1 receptor agonists (GLP-1RAs) as compared to those with similar weight followed by lifestyle management. Participants will: * Take GLP-1RA as prescribed or continue to work on lifestyle management for weight loss * Take provided calcium and vitamin D supplements * Attend 6 study visits over 24 months with two at the beginning and then every 6 months that include: * History and Physical Exams * Lab Work * Imaging studies * Questionnaires * 24-hour dietary recalls

This description comes directly from the study's public registry record.

Talk to the study team

Madhusmita Misra, MD, MPH  ·  434-924-9141  ·  madhusmita.misra@uvahealth.org

Christine Burt Solorzano, MD  ·  434-924-9084  ·  christine.burtsolorzano@uvahealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

University of Virginia Medical CenterCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06903923