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Study identifier: NCT06902740 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis

Condition: Intracranial Atherosclerosis · Intracranial Artery Stenosis · Atherosclerotic Plaque  ·  Sponsor: Peking Union Medical College Hospital

PhasePhase 4
Planned participants300
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a prospective, multicenter, open-label, blinded-endpoint, randomized controlled trial designed to evaluate the efficacy and safety of PCSK9 inhibitor combined with statin therapy compared to statin monotherapy in reversing asymptomatic intracranial atherosclerosis, assessed using high-resolution magnetic resonance imaging of the intracranial vessel walls.

This description comes directly from the study's public registry record.

Talk to the study team

Weihai Xu, MD  ·  86+13651147766  ·  xuwh@pumch.cn

Yiyang Liu, PhD  ·  86+13938912070  ·  liuyydoct@163.com

Always discuss trial participation with your own doctor first.

Locations (19)

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing, Beijing Municipality, ChinaRecruiting
Chinese PLA General HospitalBeijing, Beijing Municipality, ChinaNot Yet Recruiting
The Third Affiliated Hospital of Sun Yat-sen University, Yuedong HospitalMeizhou, Guangdong, ChinaNot Yet Recruiting
Cangzhou Hospital of Integrated Traditional Chinese and Western MedicineCangzhou, Hebei, ChinaNot Yet Recruiting
Peking University Third Hospital Qinhuangdao HospitalQinhuangdao, Hebei, ChinaNot Yet Recruiting
Hebei Provincial People's HospitalShijiazhuang, Hebei, ChinaRecruiting
Tangshan Worker's HospitalTangshan, Hebei, ChinaNot Yet Recruiting
First Affiliated Hospital of Harbin Medical UniversityHarbin, Heilongjiang, ChinaNot Yet Recruiting
The first affiliated hospital of zhengzhou universityZhengzhou, Henan, ChinaNot Yet Recruiting
Taihe HospitalShiyan, Hubei, ChinaNot Yet Recruiting
Zhongnan Hospital of Wuhan UniversityWuhan, Hubei, ChinaNot Yet Recruiting
Baotou Central HospitalBaotou, Inner Mongolia, ChinaNot Yet Recruiting

+ 7 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06902740