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Study identifier: NCT06902350 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors

Condition: Neoplasms · Glioblastoma, Adult · Small Cell Lung Carcinoma (SCLC)  ·  Sponsor: Chipscreen Biosciences, Ltd.

PhasePhase 1
Planned participants102
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This trial is a single-arm, open-label, first-in-human study of CS231295, comprising two phases: dose escalation (including single-dose and multiple-dose) and cohort expansion. The Dose-Limiting Toxicity (DLT) observation period includes 6 days for single-dose and the first cycle (28 days) for multiple-dose. The overall study consists of screening period, treatment period, and follow-up period. The primary objectives of this study are to evaluate the safety, tolerability and pharmacokinetic (PK) characteristics of CS231295 in patients with advanced solid tumors, and to recommended Phase 2 dose(s) (RP2D) of CS231295 in appropriate tumor(s).

This description comes directly from the study's public registry record.

Talk to the study team

Xinhang Wang  ·  +86 0755-36993500  ·  xinhwang@chipscreen.com

Always discuss trial participation with your own doctor first.

Locations (2)

Beijing Tiantan Hospital, Capital Medical UniversityBeijing, Beijing Municipality, ChinaNot Yet Recruiting
Jilin Cancer HospitalChangchun, Jilin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06902350