Condition: Plaque Induced Gingivitis · Halitosis · Oral Disease · Sponsor: Al-Mustansiriyah University
The present research aims to evaluate the efficiency of kefir mouthwash in enhancing oral health status by employing an in vivo experimental approach. Specifically, the study will assess how kefir mouthwash influences key oral health indicators, including gingival inflammation, plaque development, oral hygiene status, and halitosis. The study will be conducted over a 28-day period, with follow-up assessments every 14 days. The study will include systemically healthy adults with moderate gingivitis. Clinical parameters such as the Gingival Index (GI), Plaque Index (PI), and Simplified Oral Hygiene Index (OHI-S) will be measured, along with inflammatory biomarkers, including Interleukin-1β (IL-1β) and Interleukin-10 (IL-10). Halitosis will be evaluated using a Hali meter device. All of these will be measured at base line and day 14 and day 28 end of the study. Chlorhexidine 0.12% will be used as a comparative control to evaluate the efficacy of kefir mouthwash in improving oral health. This research intends to provide scientific evidence supporting the use of kefir as a probiotic-based mouthwash, offering a natural alternative to chemical mouthwashes and potentially reducing the negative consequences commonly associated with their use.
This description comes directly from the study's public registry record.
Zahra H Al-Tamimi, MS student · 009647806462936 · Zahar94@uomustansiriyah.edu.iq
Zahra H Al-Tamimi, MS student · +964 780 031 5235 · Zahar94@uomustansiriyah.edu.iq
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| Al-Mustansiriyah University/College of Dentistry | Baghdad, Iraq | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06900881