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Study identifier: NCT06900829 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

#AWARE.HIV Europe: Supporting Healthcare Professionals to Find Undiagnosed HIV in European Hospitals: An Effectiveness-implementation Trial.

Condition: HIV Infection · HIV · Stigma  ·  Sponsor: Casper Rokx

PhaseNA
Planned participants5200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The #aware.hiv Europe study is a real-world, multicenter, stepped-wedge cluster randomized, effectiveness-implementation trial designed to evaluate whether the introduction of dedicated HIV teams in hospitals can improve HIV testing rates among patients presenting with HIV indicator conditions across ten European countries. Study Design: The study employs a stepped-wedge design, whereby clusters of hospitals transition sequentially from a control phase (routine care) to an intervention phase. All patient data are collected retrospectively from routine care, while prospective data are gathered at the healthcare professional level. The project spans four years and involves hospitals from the Netherlands, Belgium, United Kingdom, Germany, Spain, France, Italy, Romania, Poland, and Ukraine. This design allows for comparison of HIV testing rates and related outcomes before and after the implementation across different settings and time points. Intervention: The core intervention involves the establishment of hospital-based HIV teams. Each team is led by an HIV specialist and supported by nurses and data collectors. Their responsibilities include: Identification and Surveillance: Screening routine electronic health records for HIV indicator conditions using predefined ICD-10 codes and verifying cases that warrant HIV testing. Audit \& Feedback: Providing targeted recommendations to treating physicians when an HIV test is indicated but has not been performed, thereby prompting…

This description comes directly from the study's public registry record.

Talk to the study team

Klaske J Vliegenthart-Jongbloed, Internist-Infectiologist, DTMH  ·  0031648382045  ·  k.vliegenthart-jongbloed@erasmusmc.nl

Marianne van Wingerden, Research nurse  ·  0031107040704  ·  aware.hiv@erasmusmc.nl

Always discuss trial participation with your own doctor first.

Locations (28)

University Hospital GhentGhent, BelgiumNot Yet Recruiting
European hospital of MarseilleMarseille, FranceRecruiting
St. Joseph Krankenhaus Berlin TempelhofBerlin, GermanyRecruiting
Charité Universitätsmedizin BerlinBerlin, GermanyRecruiting
Cologne University HospitalCologne, GermanyRecruiting
Klinikum der Technischen Universität München (TUM)München, GermanyRecruiting
Ospedale San Raffaele S.r.lMilan, ItalyRecruiting
L'Istituto Nazionale per le Malattie Infettive "L. Spallanzani" IRCCSRoma, ItalyRecruiting
Rijnstate ziekenhuisArnhem, NetherlandsRecruiting
Stichting Catharina ZiekenhuisEindhoven, NetherlandsRecruiting
University Medical Center GroningenGroningen, NetherlandsRecruiting
Stichting Maasstad ZiekenhuisRotterdam, NetherlandsRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06900829