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Study identifier: NCT06899334 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Direct Comparison of Altered States of Consciousness Induced by LSD, Psilocybin, and DMT in Healthy Participants

Condition: Healthy  ·  Sponsor: University Hospital, Basel, Switzerland

PhasePhase 1
Planned participants24
Who can joinAll sexes, 25 Years to no upper limit
Healthy volunteersYes

About this study

The primary objective of this study is to determine whether equivalent moderately high doses of LSD, psilocybin, and DMT produce qualitatively similar peak effects when the effect duration is standardized with ketanserin. A DMT infusion mimicking oral LSD and psilocybin administrations will be tested, as well as intravenously administered ketanserin.

This description comes directly from the study's public registry record.

Talk to the study team

Matthias E Liechti, Prof. Dr. MD  ·  61 328 68 68  ·  matthias.liechti@usb.ch

Mélusine Humbert-Droz, MSc  ·  61 328 48 19  ·  melusine.humbert-droz@usb.ch

Always discuss trial participation with your own doctor first.

Locations (1)

University HospitalBasel, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06899334