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Study identifier: NCT06898515 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Condition: Acute Decompensated Heart Failure  ·  Sponsor: Reprieve Cardiovascular, Inc

PhasePhase 3
Planned participants400
Who can joinAll sexes, 22 Years to no upper limit
Healthy volunteersNo

About this study

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve System to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main objective is to determine if the Reprieve System can more efficiently decongest ADHF patients in comparison to Control Therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Annemarie Forrest  ·  617-848-0400  ·  aforrest@reprievecardio.com

Always discuss trial participation with your own doctor first.

Locations (53)

University of California IrvineIrvine, California, United StatesRecruiting
Scripps Memorial HospitalLa Jolla, California, United StatesNot Yet Recruiting
UC Davis Medical CenterSacramento, California, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
Piedmont Atlanta HospitalAtlanta, Georgia, United StatesRecruiting
Piedmont Augusta HospitalAugusta, Georgia, United StatesRecruiting
Northeast Georgia Medical CenterGainesville, Georgia, United StatesRecruiting
Advocate Christ Medical CenterOak Lawn, Illinois, United StatesNot Yet Recruiting
University of Kansas Medical CenterKansas City, Kansas, United StatesRecruiting
University of Louisville HospitalLouisville, Kentucky, United StatesNot Yet Recruiting
Trinity Health Ann Arbor HospitalAnn Arbor, Michigan, United StatesRecruiting
Corewell Health Butterworth HospitalGrand Rapids, Michigan, United StatesRecruiting

+ 41 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06898515