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Study identifier: NCT06897930 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

Condition: Lupus Erythematosus, Systemic  ·  Sponsor: AstraZeneca

PhasePhase 1/Phase 2
Planned participants150
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a Phase 1b/2, single-arm, open-label, multi-center, clinical study of AZD0120, a CD19/BCMA dual CAR T cell therapy, to evaluate the safety, tolerability, and efficacy in adult participants with refractory Systemic Lupus Erythematosus.

This description comes directly from the study's public registry record.

Talk to the study team

AstraZeneca Clinical Study Information Center  ·  1-877-240-9479  ·  information.center@astrazeneca.com

Always discuss trial participation with your own doctor first.

Locations (18)

Research SiteSan Francisco, California, United StatesNot Yet Recruiting
Research SiteStanford, California, United StatesNot Yet Recruiting
Research SiteTampa, Florida, United StatesSuspended
Research SiteAtlanta, Georgia, United StatesNot Yet Recruiting
Research SiteChicago, Illinois, United StatesNot Yet Recruiting
Research SiteBethesda, Maryland, United StatesWithdrawn
Research SiteBoston, Massachusetts, United StatesRecruiting
Research SiteSt Louis, Missouri, United StatesRecruiting
Research SiteNew York, New York, United StatesRecruiting
Research SiteSyracuse, New York, United StatesRecruiting
Research SiteChapel Hill, North Carolina, United StatesRecruiting
Research SiteCharlotte, North Carolina, United StatesRecruiting

+ 6 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06897930