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Study identifier: NCT06897475 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

Condition: Type 2 Diabetes  ·  Sponsor: Eli Lilly and Company

PhasePhase 2
Planned participants240
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The purpose of this study is to measure the change in hemoglobin A1c (HbA1c) with LY3457263 compared with placebo in participants with type 2 diabetes who are not at HbA1c goal when treated with a stable dose of semaglutide or tirzepatide. Participation in the study will last about 9 months.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (60)

Helios Clinical Research - PhoenixPhoenix, Arizona, United StatesRecruiting
Wolverine Clinical TrialsSanta Ana, California, United StatesRecruiting
Renstar Medical ResearchOcala, Florida, United StatesRecruiting
Oviedo Medical ResearchOviedo, Florida, United StatesRecruiting
Balanced Life Health Care Solutions/SKYCRNGLawrenceville, Georgia, United StatesRecruiting
Physicians Research AssociatesLawrenceville, Georgia, United StatesRecruiting
Rophe Adult and Pediatric Medicine/SKYCRNGUnion City, Georgia, United StatesRecruiting
North Georgia Clinical ResearchWoodstock, Georgia, United StatesRecruiting
Elite Clinical TrialsRexburg, Idaho, United StatesRecruiting
Investigators Research GroupBrownsburg, Indiana, United StatesRecruiting
Clinical Research of PhiladelphiaPennington, New Jersey, United StatesRecruiting
NYC Research INCLong Island City, New York, United StatesRecruiting

+ 48 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06897475