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Study identifier: NCT06896747 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study

Condition: Thin Endometrial Lining · Female Infertility · Intrauterine Adhesions  ·  Sponsor: Tang-Du Hospital

PhasePhase 1/Phase 2
Planned participants90
Who can joinFemale, 20 Years to 40 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate if engineered mechanically umbilical cord-derived stem cell exosomes, or conventional umbilical cord -derived stem cell exosomes, can improve endometrial thickness in women with thin endometrium. The main questions it aims to answer are: Can exosomes delivered via subendometrial injection improve endometrial thickness or clinical pregnancy rates compared to PRP (platelet-rich plasma)? Are there significant differences in endometrial thickness between the two treatment groups? Researchers will compare the intervention groups, which one group receives mechanical exosomes and the other receives conventional esosomes via subendometrial injection, to the control group, which receives PRP via the same methods, to see if exosomes provide superior therapeutic effects. Participants will: Receive either mechanical exosomesor or conventional esosomes or PRP through subendometrial injection. Be monitored for changes in endometrial parameters.

This description comes directly from the study's public registry record.

Talk to the study team

Wanlin Zhang, PhD  ·  +86 18149363396  ·  1843678023@qq.com

Yafei Tong, MD  ·  +86 13720750251  ·  fequeo1820@126.com

Always discuss trial participation with your own doctor first.

Locations (2)

Tang-Du HospitalXi'an, Shaanxi, ChinaRecruiting
Tang-Du HospitalXi'an, Shaanxi, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06896747