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Study identifier: NCT06896227 Synced from ClinicalTrials.gov · July 29, 2026
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TAVR: The Impact of Prothesis Positioning on Valvular and Coronary Hemodynamics

Condition: Transcatheter Aortic Valve Replacement · Transcatheter Aortic Valve Implantation · Commissural Alignment  ·  Sponsor: Heinrich-Heine University, Duesseldorf

PhaseNA
Planned participants100
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The aim of this clinical study is to learn more about the effects of TAVR-prosthesis positioning on hemodynamics and the coronary arteries. The main questions it aims to answer are: 1. Does the cardiac magnetic resonance imaging and the echocardiography imaging provide an equivalent alternative to the computer tomography which is the state of the art in evaluating commissural alignment? 2. What effect does the position of the valve on the annular level have, especially its symmetrical and commissural position, on valvular and aortic blood flow characteristics? 3. What is the influence of symmetrical position and the presence of a commissural alignment on the coronary flow after transcatheter aortic valve replacement?

This description comes directly from the study's public registry record.

Talk to the study team

Tobias Zeus, Prof  ·  0211 81 18800  ·  zeus@med.uni-duesseldorf.de

Kathrin Klein, Dr. med.  ·  0211 81 08252  ·  kathrin.klein@med-uni-duesseldorf.de

Always discuss trial participation with your own doctor first.

Locations (1)

Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital DuesseldorfDüsseldorf, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06896227