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Study identifier: NCT06896188 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY)

Condition: Pancreatic Adenocarcinoma  ·  Sponsor: Anwaar Saeed

PhasePhase 1
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a study of the combination of 9 ING-41 (elraglusib) and retifanlimab plus mFOLFIRINOX in patients with pancreatic cancer without prior systemic therapy for advanced disease. The safety lead-in cohort will consist of 6 patients, followed by dose de-escalation if necessary, based on safety assessments. After evaluating the safety and tolerability at the initial dose level, the study will proceed to an expansion cohort at the determined safe dose level, with the total maximum enrollment not exceeding 12 patients for the entire study.

This description comes directly from the study's public registry record.

Talk to the study team

Debra Diecks, BSN  ·  412-623-8364  ·  diecksda@upmc.edu

Amy Rose, BSN  ·  412-647-8587  ·  kennaj@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UPMC Hillman Cancer CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06896188