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Study identifier: NCT06892210 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

Condition: Chronic Obstructive Pulmonary Disease (COPD)  ·  Sponsor: Copenhagen Respiratory Research

PhasePhase 4
Planned participants2000
Who can joinAll sexes, 40 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this cluster randomized controlled trial is to determine the optimal treatment for Acute Exacerbation of Chronic Obstructive Pulmonary Disease. The study compares the effects and side effects of hydrocortisone and prednisolone in patients above 40 years old diagnosed with chronic obstructive pulmonary disease with acute exacerbation. The main question is whether there is a difference in readmission for COPD excerbation or all cause mortality within thirty days. Participants will randomized to receive treatment with either hydrocortisone or prednisolone.

This description comes directly from the study's public registry record.

Talk to the study team

Jens-Ulrik Stæhr Jensen, MD, PHD  ·  38673057  ·  jens.ulrik.jensen@regionh.dk

Pradeesh Sivapalan, MD, PHD  ·  29880601  ·  pradeesh.sivapalan.02@regionh.dk

Always discuss trial participation with your own doctor first.

Locations (14)

Bornholm HospitalRønne, Bornholm, DenmarkRecruiting
Amager HospitalCopenhagen, Copenhagen City, DenmarkRecruiting
Bispebjerg HospitalCopenhagen, Copenhagen City, DenmarkRecruiting
Frederiksberg HospitalFrederiksberg, Copenhagen City, DenmarkRecruiting
Gentofte HospitalHellerup, Copenhagen City, DenmarkRecruiting
Herlev HospitalHerlev, Copnhagen Surroundings, DenmarkRecruiting
Hvidovre HospitalHvidovre, Copnhagen Surroundings, DenmarkRecruiting
Nordsjællands HospitalHillerød, North Zealand, DenmarkRecruiting
Holbæk SygehusHolbæk, Region Sjælland, DenmarkRecruiting
University Hospital of Region Zealand, KøgeKøge, Region Sjælland, DenmarkRecruiting
Næstved SygehusNæstved, Region Sjælland, DenmarkRecruiting
Ringsted SygehusRingsted, Region Sjælland, DenmarkRecruiting

+ 2 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06892210