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Study identifier: NCT06891456 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Pulsed Field Ablation for Post-Infarction Ventricular Tachycardia

Condition: Ventricular Tachycardia · Ischemic Heart Disease · Sustained VT  ·  Sponsor: Pasquale Santangeli

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

ASCEND is a randomized controlled open-label pilot study evaluating the safety and effectiveness of pulsed field ablation (PFA) with the novel FARAPOINT catheter compared to the standard radiofrequency (RFA) ablation with ThermoCool ST/FlexAbility SE/ThermoCool ST SF/TactiFlex SE of ventricular tachycardia (VT) in the patients with ischemic cardiomyopathy and implantable cardioverter-defibrillator (ICD). The study hypothesis is that the PFA ablation is more efficient compared to the RFA technique but retains a comparable safety profile.

This description comes directly from the study's public registry record.

Talk to the study team

Pasquale Santangeli, MD, PhD  ·  216-445-1940  ·  santanp3@ccf.org

Yuki Kuramochi, BSN, RN  ·  216-445-4063  ·  kuramoy@ccf.org

Always discuss trial participation with your own doctor first.

Locations (1)

Cleveland ClinicCleveland, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06891456