Condition: Leber Congenital Amaurosis 10 · Blindness · Leber Congenital Amaurosis · Sponsor: Laboratoires Thea
The purpose of this double-masked, randomized, placebo-controlled, paired-eye study is to evaluate the efficacy, safety and tolerability of Sepofarsen in subjects with Leber Congenital Amaurosis (LCA) due to the c.2991+1655A\>G (p.Cys998X) mutation in the CEP290.
This description comes directly from the study's public registry record.
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Always discuss trial participation with your own doctor first.
| UCSF Wayne and Gladys Valley Center for Vision | San Francisco, California, United States | Recruiting |
| University of Miami - Bascom Palmer Eye Institute | Miami, Florida, United States | Recruiting |
| University of Iowa | Iowa City, Iowa, United States | Recruiting |
| University of Minnesota Medical School | Minneapolis, Minnesota, United States | Recruiting |
| University of Pennsylvania - Center for Advanced Retinal & Ocular Therapeutics | Philadelphia, Pennsylvania, United States | Recruiting |
| Universitair Ziekenhuis Gent (UZ) | Ghent, Belgium | Recruiting |
| INRET Clínica/ Santa Casa de Misericórdia de Belo Horizonte | Belo Horizonte, Minas Gerais, Brazil | Recruiting |
| Federal University of São Paulo - Hospital São Paulo (UNIFESP-HSP) | São Paulo, São Paulo, Brazil | Recruiting |
| University of Alberta | Edmonton, Alberta, Canada | Recruiting |
| The Hospital for Sick Children - SickKids | Toronto, Ontario, Canada | Recruiting |
| Centre de maladies rares CHNO des Quinze Vingt | Paris, France | Recruiting |
| Justus-Liebig Universität - Department of Ophthalmology | Giessen, Germany | Recruiting |
+ 5 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06891443