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Study identifier: NCT06889961 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Daily Mixed Spice Consumption on Memory Function

Condition: Memory · Cognitive Function  ·  Sponsor: University of California, Los Angeles

PhaseNA
Planned participants50
Who can joinAll sexes, 50 Years to 80 Years
Healthy volunteersYes

About this study

The aging process entails a multitude of structural and functional alterations within the brain, culminating in a gradual and progressive decline in cognitive function. Recent research has indicated that various spices may hold the key to enhancing brain health and combating the effects of aging on cognitive abilities. The hypothesis is that a mixture of spices, acknowledged for their reported memory protection potential, may yield a more potent beneficial effect on memory function than a single spice. The spice mixture will be used at culinary dose, and therefore side effects are anticipated. In this study, the effects of spice mixture will be evaluated, as well as their anti-oxidant, and anti-inflammatory properties. The proposed pilot study will include 50 adults (ages 50-80), exhibiting typical age-related mild cognitive decline, excluding dementia or major neurocognitive disorders. They will be randomized 1:1 assigned into a daily intake of either 4.00 g spice mixture capsules or 4.00 g maltodextrin capsules over 3 months, and explore the sustainable effect over 3 additional months. The changes in symptoms of cognition, fatigue, and mood symptoms of the spice group vs. placebo group will be compared. The outcome of the investigation of the effects of mixed spice consumption will provide important novel information on dietary recommendation of spice to preserve cognitive function in aging population.

This description comes directly from the study's public registry record.

Talk to the study team

Hila Zelicha, RD PHD  ·  +1-310-206-8292  ·  uclanutrition@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

UCLA Center for Human NutritionLos Angeles, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06889961