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Study identifier: NCT06889766 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma

Condition: Advanced Melanoma · Melanoma Metastatic · Sarcoma  ·  Sponsor: Centre Hospitalier Universitaire Vaudois

PhasePhase 1
Planned participants9
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A single center, dose escalaion, Phase I clinical trial to demonstrate safety and efficacy of LauT-1, autologous "New York Esophageal Squamous Cell Carcinoma-1 T-Cell Receptor (NY-ESO-1 TCR)-directed T cells in combination with non-myeloablative (NMA) lymphodepleting chemotherapy and low dose irradiation (LDI) in patients with NY-ESO-1 positive sarcoma and melanoma.

This description comes directly from the study's public registry record.

Talk to the study team

Bernhard Gentner, MD  ·  +4179 556 90 20  ·  Bernhard.Gentner@chuv.ch

Virginie Zimmer, Study Coordinator  ·  +41 21 314 97 09  ·  virginie.zimmer@chuv.ch

Always discuss trial participation with your own doctor first.

Locations (2)

Centre Hospitalier Universitaire Vaudois (CHUV)Lausanne, Canton of Vaud, SwitzerlandNot Yet Recruiting
Centre Hospitalier Universitaire VaudoisLausanne, Canton of Vaud, SwitzerlandRecruiting

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Source record: clinicaltrials.gov/study/NCT06889766