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Study identifier: NCT06889701 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Phase 1/2 Study to Evaluate the Safety, PK and Efficacy of TNP-2092 Administered Via IA Injection in PJI Participants

Condition: Periprosthetic Joint Infection (PJI)  ·  Sponsor: TenNor Therapeutics Inc.

PhasePhase 1/Phase 2
Planned participants33
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 1/2, randomized, controlled, open-label, proof-of-concept study to evaluate the safety and tolerability, local and systemic PK profiles of TNP-2092 administered via IA injection on the basis of vancomycin IV and oral antibiotics therapy in participants with early (within 1 month of TKA) or acute hematogenous (within 3 weeks of infectious symptoms) PJI requiring or not requiring DAIR therapy after TKA, or requiring long-term antibiotic suppression therapy for PJI (including PJI occurring after various joint replacements and revision surgeries).

This description comes directly from the study's public registry record.

Talk to the study team

Li Cao  ·  +86 991-4366553  ·  xjbone@sina.com

Jing Chen  ·  +86 512 86861979  ·  jing.chen@tennorx.com

Always discuss trial participation with your own doctor first.

Locations (1)

The First Affiliated Hospital of Xinjiang Medical UniversityÜrümqi, Xinjiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06889701