Condition: Triple Negative Breast Cancer Metastatic · Melanoma Metastatic · Colorectal Cancer Metastatic · Sponsor: Fudan University
This study focuses on the treatment of liver metastases from three common cancers: colorectal cancer, triple-negative breast cancer and melanoma. Currently, there are limitations in the treatment of liver metastases of these cancers. Multimodal thermophysical ablation therapy can reshape the tumor microenvironment, release neoantigens, and act as an in-situ vaccine. On this basis, the combination of multimodal ablation with immunotherapeutic drugs such as pucotenlimab will be explored. The efficacy and safety of this combination therapy in patients with liver metastases of solid tumors will be investigated, with the expectation of breaking through the existing treatment limitations.
This description comes directly from the study's public registry record.
Hongxia Wang, MD · +86 021-64175590 · wanghongxia@shca.org.cn
Wentao Li, MD
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| Fudan University Shanghai Cancer Center | Shanghai, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06889610