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Study identifier: NCT06888843 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study to Evaluate the Use of Capecitabine in Monotherapy and in Combination With Oxaliplatin in Elderly Patients as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer.

Condition: Colorectal Cancer  ·  Sponsor: Nizhny Novgorod Regional Clinical Oncology Center

PhasePhase 2
Planned participants160
Who can joinAll sexes, 70 Years to 90 Years
Healthy volunteersNo

About this study

All patients with locally advanced colorectal cancer after radical surgical intervention who have not previously received systemic antitumor treatment will be randomized into two groups receiving fluoropyrimidines in mono-regimen and in combination with oxaliplatin. Main objectives: * to compare the 3-year disease-free survival and 5-year overall survival rates in the two groups. * to identify, through a comprehensive geriatric assessment among elderly patients, the groups that benefit most from adjuvant chemotherapy. Patients will be treated until progression of the process is detected or the maximum effect of therapy is reached (the longest duration of treatment is 6 months).

This description comes directly from the study's public registry record.

Talk to the study team

Arina Datsyuk  ·  +79049209496  ·  doc70doc@yandex.ru

MIKHAIL OSIPOV  ·  +79052075653  ·  ocipovmixail@mail.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Research Institute of Clinical Oncology "Nizhny Novgorod Regional Clinical Oncological Dispensary"Nizhny Novgorod, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT06888843