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Study identifier: NCT06887803 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Roginolisib in Combination With Ruxolitinib in Patients With Myelofibrosis (MF) Who Are Unresponsive to JAK Inhibitors

Condition: Myelofibrosis (MF)  ·  Sponsor: iOnctura

PhasePhase 1/Phase 2
Planned participants26
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn how roginolisib works in comparison to standard treatment in adult patients with Myelofibrosis. The main questions it aims to answer is to evaluate the safety and tolerability of roginolisib when administered in combination with ruxolitinib.

This description comes directly from the study's public registry record.

Talk to the study team

Tracey Hammett, RN  ·  +44 7776498978  ·  t.hammett@ionctura.com

Karen Tonge  ·  +44 7770678446  ·  k.tonge@ionctura.com

Always discuss trial participation with your own doctor first.

Locations (12)

Azienda Ospedaliero Universitaria Careggi Firenze, Struttura Complessa di EmatologiaFlorence, Florence, ItalyRecruiting
IRCCS Clinical Institute HumanitasRozzano, Milan, ItalyRecruiting
Istituto di Ematolgia e Oncologia MedicaBologna, ItalyRecruiting
Istituto Romagnolo per lo Studio dei TumoriMeldola, ItalyRecruiting
Azienda Sanitario Universitaria Friuli CentraleUdine, ItalyRecruiting
Vall d'Hebron University HospitalBarcelona, SpainRecruiting
Avigunda Gran via de l'Hospitalet 199-203, 08908 L'Hospitalet de LlobregatBarcelona, SpainRecruiting
START Madrid CIOCCMadrid, SpainRecruiting
Hospital Universitario de SalamancaSalamanca, SpainRecruiting
United Lincolnshire Teach Hospitals NHS Trust, Pilgrim Hospital BostonBoston, Lincolnshire, United KingdomRecruiting
Belfast City HospitalBelfast, United KingdomRecruiting
Guy´s and St. Thomas NHS Foundation TrustLondon, United KingdomNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT06887803