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Study identifier: NCT06886451 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Vomiting Prevention in Children With Cancer

Condition: Chemotherapy Induced Nausea and Vomiting · Quality of Life (QOL) · Pediatric Cancer  ·  Sponsor: The Hospital for Sick Children

PhaseNA
Planned participants1332
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients. The main questions it aims to answer are whether an ML model predicting the risk of vomiting within the next 96 hours will: Primary 1\. Reduce the proportion with any vomiting within the 96-hour window Secondary 1. Reduce the number of vomiting episodes 2. Increase the proportion receiving care pathway-consistent care 3. Impact on number of administrations and costs of antiemetic medications Newly admitted participants will have a ML model predict the risk of vomiting within the next 96 hours according to their medical admission information. The prediction will be made at 8:30 AM following admission. Pharmacists will be charged with bringing information about patients' vomiting risk to the attention of the medical team and implementing interventions.

This description comes directly from the study's public registry record.

Talk to the study team

Lillian Sung, MD, PhD  ·  416-813-5287  ·  lillian.sung@sickkids.ca

Agata Wolochacz, BMSc  ·  416-813-7654  ·  agata.wolochacz@sickkids.ca

Always discuss trial participation with your own doctor first.

Locations (1)

The Hospital for Sick ChildrenToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06886451