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Study identifier: NCT06885710 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

HBV-Specific TCR-T Cell Therapy Combined With Nucleos(t)Ide Analogues in Chronic Hepatitis B Patients

Condition: Chronic Hepatitis b  ·  Sponsor: Changhai Hospital

PhasePhase 1
Planned participants19
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersNo

About this study

This is a open-label study to evaluate the safety and efficacy of autologous T-cells transfected with messenger ribonucleic acid (mRNA) encoding Hepatitis-B virus (HBV) antigen specific T cell receptor (TCR) in combination with nucleos(t)ide analogues (NAs) in HBeAg-positive and negative chronic hepatitis B patients.

This description comes directly from the study's public registry record.

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Locations (1)

Changhai HospitalShanghai, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06885710