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Study identifier: NCT06885255 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of Intermittent Fasting and Exercise on Inflammation, Metabolism, and the Microbiome in Metabolic Syndrome

Condition: Metabolic Syndrome · Obesity and Obesity-related Medical Conditions  ·  Sponsor: University of Erlangen-Nürnberg Medical School

PhaseNA
Planned participants250
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

The goal of this intervention trial is to assess the effects of intermittent fasting, both alone and in combination with high-intensity interval training, on patients with obesity and metabolic syndrome. The main question it aims to answer is: Does intermittent fasting, with or without high-intensity interval training, reduce chronic inflammation in patients with obesity and metabolic syndrome? Participants will follow an intermittent fasting regime for 3 months, with one intervention group additionally participating in high-intensity interval training twice a week. In addition, there are two control groups: one consisting of participants with metabolic syndrome and one consisting of generally healthy individuals. The study includes a 3-month intervention phase followed by a 3-month follow-up phase. During the 6-month study period, all participants will attend 6 in-house study visits and 2 phone visits, during which they will undergo assessments and receive nutritional counseling.

This description comes directly from the study's public registry record.

Talk to the study team

Prof. Dr. med. Yurdagül Zopf  ·  0049091318545220  ·  yurdaguel.zopf@uk-erlangen.de

Always discuss trial participation with your own doctor first.

Locations (1)

Hector-Center for Nutrition, Exercise and Sports, University Hospital ErlangenErlangen, Bavaria, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT06885255