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Study identifier: NCT06885125 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dietary Intervention to Improve Fertility in Women With Endometriosis Undergoing IVF

Condition: Endometriosis  ·  Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

PhaseNA
Planned participants438
Who can joinFemale, 18 Years to 39 Years
Healthy volunteersNo

About this study

The goal of this randomized controlled trial is to assess whether a 12-week anti-inflammatory diet can improve fertility outcomes in women with endometriosis undergoing In Vitro Fertilization (IVF). The main questions are: * Does the anti-inflammatory diet reduce the rate of inadequate ovarian response to hormonal stimulation (retrieval of ≤3 oocytes)? * Does it improve secondary outcomes such as embryo quality, pregnancy rates, inflammation markers, and quality of life? Researchers will compare two groups: * Women receiving standard IVF protocols. * Women undergoing the same IVF protocol plus the anti-inflammatory diet. Participants will: * Be randomized into one of the two groups. * Follow dietary counseling sessions and complete dietary assessments (diet group). * Provide biological samples (e.g., plasma, vaginal and fecal swabs, and follicular fluid) before and after the dietary intervention to evaluate potential differences in inflammation, hormonal levels, and microbiome composition between the two groups and across timepoints (pre- and post-diet). * Complete questionnaires on quality of life, sexual function, and symptomatology severity before and after the intervention to assess differences between the two groups and across timepoints.

This description comes directly from the study's public registry record.

Talk to the study team

Paola Vigano', PhD  ·  +390255034302  ·  paola.vigano@policlinico.mi.it

Marco Reschini, MSc  ·  +390255034303  ·  marco.reschini@policlinico.mi.it

Always discuss trial participation with your own doctor first.

Locations (1)

Fondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoMilan, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06885125