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Study identifier: NCT06884358 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Functional Capacity in Anderson-Fabry Disease Patients

Condition: Anderson-Fabry Disease  ·  Sponsor: IRCCS Policlinico S. Donato

PhaseN/A
Planned participants100
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to observe the relation between excercise parameters - assessed by CPET - and rest/stress hemodynamic parameters - assessed by echocardiogram and CMR - in patients with a genetic diagnosis of Anderson-Fabry Disease. Participants will undergo: * baseline evaluation: clinical evaluation, disease staging with FASTEX and MSSI, KCCQ for quality of life assessment, resting 12-leads ECG, 6MWT, CPET-ESE and contrast-enhanced CMR; * before 36 months from baseline: resting 12-leads ECG, 2D rest and stress echocardiogram, CPET-ESE, contrast-enhanced CMR, disease staging with FASTEX and MSSI and KCCQ for quality of life assessment; * up to 7 years from baseline: clinical follow-up.

This description comes directly from the study's public registry record.

Talk to the study team

Massimo Piepoli, MD, PhD  ·  +39 0252774942  ·  massimo.piepoli@grupposandonato.it

Gianluigi Guida, MD  ·  +39 0252774942  ·  gianluigi.guida@grupposandonato.it

Always discuss trial participation with your own doctor first.

Locations (5)

Spedali Civili HospitalBrescia, Brescia, ItalyActive Not Recruiting
Fondazione IRCCS Ca' Granda Ospedale Maggiore PoliclinicoMilan, Milan, ItalyActive Not Recruiting
IRCCS Policlinico San DonatoSan Donato Milanese, Milan, ItalyRecruiting
Fondazione IRCCS San Gerardo dei TintoriMonza, Monza, ItalyActive Not Recruiting
Regina Margherita HospitalTurin, Turin, ItalyActive Not Recruiting

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Source record: clinicaltrials.gov/study/NCT06884358