Condition: Alzheimer Disease · Sponsor: RenJi Hospital
The goal of this observational study is to learn about the efficacy of Lecanemab treatment for early-onset familial Alzheimer's disease (AD) in patients under 65 years of age with a family history of AD. Participants will receive Lecanemab at a dosage of 10 mg/kg every two weeks for a total of 18 months and will undergo cognitive assessments, PET and MRI scans, blood/fluid tests and whole genome sequencing. The study will explore the effects of genetic and hereditary factors on the efficacy of Lecanemab treatment in early-onset familial AD patients.
This description comes directly from the study's public registry record.
Jinwen Xiao · +86 13917310784 · jw_xiao78@163.com
Always discuss trial participation with your own doctor first.
| Xuanwu Hospital, Capital Medical University | Beijing, China, China | Recruiting |
| The Second Affiliated Hospital of Guangzhou Medical University | Guangdong, China, China | Recruiting |
| The Affiliated Hospital of Guizhou Medical University | Guizhou, China, China | Recruiting |
| Nanjing Brain Hospital | Jiangsu, China, China | Recruiting |
| Nanjing Drum Tower Hospital | Jiangsu, China, China | Recruiting |
| Nantong First People's Hospital | Jiangsu, China, China | Recruiting |
| Huadong Hospital, Fudan University | Shanghai, China, China | Recruiting |
| Renji Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai, China, China | Recruiting |
| Ruijin Hospital, Shanghai Jiao Tong University School of Medicine | Shanghai, China, China | Recruiting |
| Shanghai Mental Health Center | Shanghai, China, China | Recruiting |
| West China Hospital of Sichuan University | Sichuan, China, China | Recruiting |
| Tianjin Medical University General Hospital | Tianjin, China, China | Recruiting |
+ 3 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06883019