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Study identifier: NCT06881784 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

Condition: NSCLC (Non-small Cell Lung Cancer) · Non-Small Cell Lung Cancer · NSCLC  ·  Sponsor: Revolution Medicines, Inc.

PhasePhase 3
Planned participants590
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to evaluate the safety and efficacy of a novel RAS(ON) inhibitor compared to docetaxel.

This description comes directly from the study's public registry record.

Talk to the study team

Revolution Medicines Study Director  ·  1-844-2-REVMED  ·  medinfo@revmed.com

Always discuss trial participation with your own doctor first.

Locations (152)

Alabama OncologyBirmingham, Alabama, United StatesRecruiting
MemorialCare Long Beach Medical CenterLong Beach, California, United StatesRecruiting
Yale University, Smillow Cancer CenterNew Haven, Connecticut, United StatesRecruiting
Florida Cancer Specialists & Research Institute - SouthFort Myers, Florida, United StatesRecruiting
BRCR GlobalPlantation, Florida, United StatesRecruiting
Cancer Care Centers of BreevardRockledge, Florida, United StatesRecruiting
Florida Cancer Specialists & Research Institute - NorthSt. Petersburg, Florida, United StatesRecruiting
Cleveland Clinic Martin NorthStuart, Florida, United StatesRecruiting
Florida Cancer Specialists & Research Institute - EastWest Palm Beach, Florida, United StatesRecruiting
University Cancer and Blood CenterAthens, Georgia, United StatesRecruiting
Piedmont Healthcare, IncAtlanta, Georgia, United StatesRecruiting
Winship Cancer InstituteAtlanta, Georgia, United StatesRecruiting

+ 140 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06881784