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Study identifier: NCT06881771 Synced from ClinicalTrials.gov · July 28, 2026
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FECD-TRACE: Fuchs' Endothelial Corneal Dystrophy TRAjectory and Correlation With Genotype in the United Kingdom

Condition: Fuchs Dystrophy · Fuchs' Endothelial Dystrophy · Fuchs' Endothelial Corneal Dystrophy of Bilateral Eyes  ·  Sponsor: University College, London

PhaseN/A
Planned participants500
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

FECD-TRACE is an integral component of a large research program dedicated to Fuchs Endothelial Corneal Dystrophy (FECD) in the United Kingdom. This longitudinal, observational study aims to comprehensively characterize a cohort of younger research participants who have a genetic predisposition to developing FECD. By utilizing advanced anterior segment imaging techniques, the study will monitor these individuals over a span of several years, capturing phenotypic changes that reflect the progression of the disease. Concurrently, genetic biomarkers will be examined to establish correlations with the observed phenotypic changes. The primary objective of FECD-TRACE is to enhance our understanding of the intricate genetic mechanisms underlying FECD and establish connections between these genetic findings and clinical outcomes. Ultimately, this research strives to facilitate the development of personalized care approaches for individuals affected by FECD.

This description comes directly from the study's public registry record.

Talk to the study team

Siyin Liu, MBChB  ·  +44207 253 3411  ·  siyin.liu@ucl.ac.uk

Always discuss trial participation with your own doctor first.

Locations (1)

University College LondonLondon, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT06881771