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Study identifier: NCT06880029 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Circadian Rhythm Impact on TNBC Response to Neoadjuvant Immunotherapy

Condition: Triple Negative Breast Cancer (TNBC)  ·  Sponsor: Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.

PhasePhase 1/Phase 2
Planned participants20
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

CIRCADIAN is a prospective randomized clinical trial designed to evaluate the impact of pembrolizumab infusions' time-of-day on pathological complete response (pCR) rate among TNBC patients undergoing neoadjuvant treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Alexandra P. Guedes, Medical Oncologist M.D.  ·  +351968957977  ·  alexandra95dg@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Centro Hospitalar Vila Nova de Gaia/EspinhoVila Nova de Gaia, Região, PortugalRecruiting

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Source record: clinicaltrials.gov/study/NCT06880029