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Study identifier: NCT06876662 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Condition: Chronic Lymphocytic Leukemia · Non-Hodgkin Lymphoma  ·  Sponsor: Eli Lilly and Company

PhasePhase 4
Planned participants279
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed originator study, clinical study LOXO-BTK-18001/J2N-OX-JZNA. Participants in the originator study will have the opportunity to continue their assigned study intervention or continue their follow-up visits by transitioning to this study. This study will evaluate the long-term safety and efficacy of pirtobrutinib.

This description comes directly from the study's public registry record.

Talk to the study team

Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or  ·  1-317-615-4559  ·  LillyTrials@Lilly.com

Physicians interested in becoming principal investigators please contact  ·  clinical_inquiry_hub@lilly.com

Always discuss trial participation with your own doctor first.

Locations (36)

Sylvester Comprehensive Cancer CenterMiami, Florida, United StatesRecruiting
Florida Cancer SpecialistsSarasota, Florida, United StatesRecruiting
The Emory ClinicAtlanta, Georgia, United StatesRecruiting
Northwestern UniversityChicago, Illinois, United StatesRecruiting
Dana-Farber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Mayo Clinic- MinnesotaRochester, Minnesota, United StatesRecruiting
University Of Nebraska Medical CenterOmaha, Nebraska, United StatesRecruiting
Cayuga Cancer CenterIthaca, New York, United StatesActive Not Recruiting
Northwell HealthLake Success, New York, United StatesRecruiting
Memorial Sloan-Kettering Cancer Center (MSKCC) - New YorkNew York, New York, United StatesRecruiting
Memorial Sloan-Kettering Cancer Center (MSKCC) - New YorkNew York, New York, United StatesActive Not Recruiting
Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

+ 24 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06876662