● Recruiting

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Condition: Carcinoma, Non-Small-Cell Lung · Sponsor: Mirati Therapeutics Inc.

PhasePhase 3

Planned participants630

Who can joinAll sexes, 18 Years to no upper limit

Healthy volunteersNo

About this study

This is a trial to evaluate the efficacy, safety, and tolerability of adagrasib plus pembrolizumab plus platinum-doublet chemotherapy versus placebo plus pembrolizumab plus platinum-doublet chemotherapy in participants with previously untreated, locally advanced or metastatic NSCLC with KRAS G12C mutation

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com · 855-907-3286 · Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (351)

Local Institution - 0347	Birmingham, Alabama, United States	Not Yet Recruiting
Local Institution - 0686	Springdale, Arkansas, United States	Not Yet Recruiting
Local Institution - 0581	Fullerton, California, United States	Not Yet Recruiting
Local Institution - 0682	Loma Linda, California, United States	Not Yet Recruiting
Helios Clinical Research	Long Beach, California, United States	Recruiting
Local Institution - 0442	Denver, Colorado, United States	Not Yet Recruiting
Medical Oncology Hematology Consultants, PA	Newark, Delaware, United States	Recruiting
Local Institution - 0694	Clearwater, Florida, United States	Not Yet Recruiting
Cancer Specialists of North Florida	Jacksonville, Florida, United States	Recruiting
Local Institution - 0696	Miami, Florida, United States	Not Yet Recruiting
Local Institution - 0680	Ocala, Florida, United States	Not Yet Recruiting
Mid Florida Hematology and Oncology Center	Orange City, Florida, United States	Recruiting

+ 339 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT06875310