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Study identifier: NCT06874192 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of LOw DOse COlchicine in Patients With STatin INTolerance: the LODOCO STINT Pilot Study

Condition: Statin Adverse Reaction  ·  Sponsor: Virginia Commonwealth University

PhasePhase 1
Planned participants30
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

Statins are a class of cholesterol lowering medications that contribute to reducing a person's risk of experiencing a cardiovascular event like heart attack. Along with the ability to lower cholesterol, statins also possess anti-inflammatory properties which contribute to their cardioprotective effects. Some people experience side effects while taking statins and are unable to continue treatment with them,which can then increase a person's risk of having cardiovascular issues due to untreated high cholesterol levels. Prior studies have shown that inflammation in the body may lead to an increased risk of a future cardiovascular events. Low dose colchicine (LODOCO), an anti-inflammatory agent, has been shown to reduce cardiovascular events by inhibiting inflammation, a major cause of cardiovascular disease. The United States Food and Drug Administration (FDA) has approved LODOCO to reduce the risk of a future cardiac events for those who have existing heart disease or possess multiple risk factors for heart disease.

This description comes directly from the study's public registry record.

Talk to the study team

Emily Federmann  ·  804-828-3299  ·  Emily.Federmann@vcuhealth.org

Joshua West  ·  804.628.3981  ·  Joshua.West@vcuhealth.org

Always discuss trial participation with your own doctor first.

Locations (1)

Virginia Commonwealth UniversityRichmond, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT06874192