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Study identifier: NCT06873100 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Efficacy, Safety and Immunological Evaluation of Upadacitinib for Relapsing Polychondritis

Condition: Relapsing Polychondritis  ·  Sponsor: Peking University People's Hospital

PhasePhase 1/Phase 2
Planned participants30
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Relapsing polychondritis (RP) is a rare, systemic autoimmune disorder characterized by episodic inflammation of cartilaginous structures. The goal of this clinical trial is to learn if drug Upadacitinib works to treat relapsing polychondritis in adults. It will also learn about the safety of drug Upadacitinib. The main questions it aims to answer are: * Does drug Upadacitinib reduce the disease activity of relapsing polychondritis? * What medical problems do participants have when taking drug Upadacitinib? Researchers will compare drug Upadacitinib to conventional therapies (treatment with corticosteroids combined with immunosuppressants) to see if drug Upadacitinib works to treat relapsing polychondritis. Participants will: * Take drug Upadacitinib or corticosteroids combined with immunosuppressants every day for 24 weeks. * Visit the hospital once every month for checkups and tests. This clinical study will explore the efficacy and immunological evaluation of Upadacitinib in the treatment of RP.

This description comes directly from the study's public registry record.

Talk to the study team

Yifan Wu  ·  +8618766399762  ·  2411210283@stu.pku.edu.cn

Jing He  ·  +8618611707347  ·  hejing1105@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Department of Rheumatology and Immunology, Peking University People's HospitalBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06873100