Condition: Psoriatic Arthritis · Sponsor: AbbVie
Psoriatic arthritis (PsA) is a type of arthritis that happens when the body's immune system attacks healthy cells and tissues causing joint pain, stiffness, and swelling. Symptoms can get worse and go away for periods of time. This study will evaluate the efficacy and safety of targeted therapies through a series of substudies, for the treatment of active psoriatic arthritis and to assess the changes in disease symptoms. The therapies being assessed in this sub-study are risankizumab and lutikizumab. Participants will be randomized in a 1:1:1 ratio to one of the three treatment arms: lutikizumab monotherapy, risankizumab monotherapy or a combination therapy of lutikizumab and risankizumab. Around 120 participants will be enrolled in the study at approximately 40 sites worldwide. There may be higher treatment burden for participants in this trial compared to their standard of care (due to study procedures). Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.
This description comes directly from the study's public registry record.
ABBVIE CALL CENTER · 844-663-3742 · abbvieclinicaltrials@abbvie.com
Always discuss trial participation with your own doctor first.
| Newport Huntington Medical Group /ID# 272764 | Huntington Beach, California, United States | Recruiting |
| Highlands Advanced Rheumatology And Arthritis Center - Avon Park /ID# 273085 | Avon Park, Florida, United States | Recruiting |
| Clinical Research Of West Florida - Phase I Unit /ID# 273198 | Clearwater, Florida, United States | Recruiting |
| HMD Research LLC /ID# 273086 | Orlando, Florida, United States | Recruiting |
| West Broward Rheumatology Associates /ID# 272892 | Tamarac, Florida, United States | Recruiting |
| Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 273199 | Tampa, Florida, United States | Recruiting |
| Clinic Of Dr. Robert Hozman/Clinical Investigation Specialists, Inc /ID# 272879 | Skokie, Illinois, United States | Recruiting |
| Willow Rheumatology and Wellness, PLLC /ID# 277354 | Willowbrook, Illinois, United States | Recruiting |
| Klein And Associates /ID# 272829 | Hagerstown, Maryland, United States | Completed |
| Paramount Medical Research and Consulting /ID# 272757 | Middleburg Heights, Ohio, United States | Recruiting |
| Altoona Center For Clinical Research /ID# 272593 | Duncansville, Pennsylvania, United States | Recruiting |
| Private Practice - Dr. Ramesh C. Gupta I /ID# 272897 | Memphis, Tennessee, United States | Recruiting |
+ 25 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT06865105