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Study identifier: NCT06864234 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Effect of Beta-blockers on Coronary Flow and Resistance in Patients With ANOCA

Condition: Coronary Arterial Disease (CAD) · Angina (Stable) · Microvascular Circulation  ·  Sponsor: VZW Cardiovascular Research Center Aalst

PhasePhase 4
Planned participants46
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this clinical trial is to learn whether beta-blockers can improve coronary blood flow and reduce resistance in patients with angina and no obstructive coronary arteries (ANOCA). The main questions it aims to answer are: * Do beta-blockers improve coronary blood flow in patients with ANOCA? * Do beta-blockers reduce coronary microvascular resistance in these patients? Researchers will compare a beta-blocker to a placebo to see if the medication has measurable effects on coronary circulation. Participants will: * Receive a beta-blocker or a placebo * Undergo specialized heart tests (such as coronary flow and resistance measurements) before and after treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Adriaan Wilgenhof, MD  ·  +32 53 72 44 39  ·  adriaan.wilgenhof@azorg.be

Thabo Mahendiran, MD  ·  thabo.mahendiran@doctors.org.uk

Always discuss trial participation with your own doctor first.

Locations (1)

OLV Cardiovascular Center AalstAalst, Flanders, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT06864234