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Study identifier: NCT06863740 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Using Cannabis to Treat Restless Legs Syndrome

Condition: Restless Leg Syndrome (RLS)  ·  Sponsor: Sunnybrook Health Sciences Centre

PhaseNA
Planned participants30
Who can joinAll sexes, 25 Years to no upper limit
Healthy volunteersNo

About this study

Restless Legs Syndrome (RLS) is a disorder that causes painful and uncomfortable sensations in the legs, and its symptoms have a significant impact on sleep and quality of life. Cannabis has been used by some RLS patients as a treatment due to its painkilling and drowsiness effects, however there has never been a clinical research trial investigating cannabis in patients with RLS. A controlled trial is needed to establish how safe and feasible cannabis is as a treatment for RLS. The investigators plan to randomize 30 participants with moderate-to-severe RLS to receive either cannabis or placebo for 8 weeks. The investigators will measure patients sleep quality and quality of life at baseline and 8-week follow-up. The investigators will also monitor patients for any adverse reactions to the study drug.

This description comes directly from the study's public registry record.

Talk to the study team

Mark Boulos, MD  ·  416-480-4473  ·  mark.boulos@sunnybrook.ca

Always discuss trial participation with your own doctor first.

Locations (2)

Sunnybrook Health Sciences CentreToronto, Ontario, CanadaRecruiting
University Health NetworkToronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT06863740