Condition: B-cell Acute Lymphoblastic Leukemia · Sponsor: Children's Hospital Medical Center, Cincinnati
The goal of this clinical trial is to learn if the combination of drugs Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone (IoVeX) are safe to treat relapsed B-cell Acute Lymphoblastic Leukemia (B-ALL) in pediatric and adult patients. It will also learn if these drugs are well tolerated. The main questions it aims to answer are: Is the drug combination of Inotuzumab Ozogamicin, Venetoclax, and Dexamethasone (IoVeX) safe when given to patients? What medical problems do patients taking IoVeX experience? Participants will: Receive this combination of drugs for 1 cycle which is 28 days at various timepoints. If participants tolerate cycle 1 they will be eligible to continue to cycle 2 which is also 28 days. Have checkups and tests at the beginning of the study and throughout the course of each cycle.
This description comes directly from the study's public registry record.
Jeremy Rubinstein, MD, PhD · 513-636-2799 · jeremy.rubinstein@cchmc.org
Site Primary Contact Cancer line · 513-636-2799 · cancer@cchmc.org
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| Cincinnati Children's Hospital Medical Center | Cincinnati, Ohio, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06863259