Condition: Kidney Disease, Chronic · Renal Insufficiency, Chronic · Gut Dysbiosis · Sponsor: Mansoura University
The goal of this clinical trial is to learn whether probiotic supplementation can slow disease progression in patients with moderate to severe chronic kidney disease (CKD). The trial will also assess the safety of probiotics in these patients. The main questions the study aims to answer are: Does probiotic supplementation improve kidney function by reducing serum creatinine levels and protein in urine? Does it reduce inflammation and metabolic imbalances in CKD patients? Does it affect gut microbiota composition and lower harmful toxins in the body? Is probiotic supplementation safe and well-tolerated in CKD patients? Participants will: Be randomly assigned to receive either probiotics or a placebo for 6 months. Have clinic visits every 6 months for checkups, blood tests, and urine tests. Be monitored for any side effects and changes in kidney function. Researchers will compare the probiotic group to the placebo group to determine whether probiotics are effective in slowing CKD progression.
This description comes directly from the study's public registry record.
Samar Elshahat Saleh · 00201023771331 · samarelshahat@mans.edu.eg
Always discuss trial participation with your own doctor first.
| Urology and Nephrology Center, Mansoura University | Al Mansurah, Dakahliya, Egypt | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06863194