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Study identifier: NCT06862596 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy

Condition: Spinal and Bulbar Muscular Atrophy  ·  Sponsor: Masahisa Katsuno

PhasePhase 2/Phase 3
Planned participants68
Who can joinMale, 18 Years to 80 Years
Healthy volunteersNo

About this study

The purpose of this clinical trial is to evaluate the efficacy and safety of mexiletine hydrochloride in patients with spinal and bulbar muscular atrophy. The main questions it aims to answer are: Does mexiletine hydrochloride improve the ALSFRS-R score in spinal and bulbar muscular atrophy patients? Participants will: Take mexiletine hydrochloride or a placebo every day for 3 months Visit the hospital once every 4 weeks for evaluations.

This description comes directly from the study's public registry record.

Talk to the study team

Masahisa Katsuno, PhD, MD  ·  +81527442389  ·  katsuno.masahisa.i1@f.mail.nagoya-u.ac.jp

Shinobu Shimizu, PhD  ·  +81527442942  ·  shimizu.shinobu.w3@f.mail.nagoya-u.ac.jp

Always discuss trial participation with your own doctor first.

Locations (5)

Tokyo University HospitalBunkyō City, JapanRecruiting
Chiba University HospitalChiba, JapanRecruiting
Hokkaido University HospitalSapporo, JapanRecruiting
Jichi Medical University HospitalShimotsuke, JapanRecruiting
Osaka University HospitalSuita, JapanRecruiting

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Source record: clinicaltrials.gov/study/NCT06862596