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Study identifier: NCT06861387 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Cryo Nerve Block Trial

Condition: Intercostal Nerve Block · Cryo Analgesia · Minimally Invasive Lung Surgery  ·  Sponsor: St. Antonius Hospital

PhaseNA
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Background: Minimally invasive lung surgery, such as video-assisted thoracoscopic surgery (VATS) or robot-assisted thoracoscopic surgery (RATS), has become more common for lung resections because it leads to faster recovery, less pain, and shorter hospital stays. However, pain after surgery remains a major issue. Current guidelines suggest using a combination of pain management strategies to reduce the use of opioids and their side effects. Intercostal cryo-analgesia (ICCA), a technique that uses cold to reduce nerve activity, may help lower pain and opioid use after surgery. However, there is limited research on ICCA, with most studies having small sample sizes and lacking randomized controlled trials. More research is needed to compare ICCA with standard pain management in patients undergoing minimally invasive lung surgery. Objective: The goal of this study is to determine whether ICCA improves recovery compared to standard pain management after minimally invasive lung surgery. The investigators aim to measure recovery time and quality using the Quality of Recovery-15 (QoR-15) questionnaire. The investigators expect that ICCA will result in better recovery, less pain, reduced opioid use, and shorter hospital stays, without increasing the risk of nerve damage or other complications. Study Design: This will be a single-center, blinded, randomized controlled trial, along with an observational registry. Study Population: The study will include adults who are undergoing …

This description comes directly from the study's public registry record.

Talk to the study team

Bart Köhlen  ·  +31 88 320 1108  ·  b.kohlen@antoniusziekenhuis.nl

Always discuss trial participation with your own doctor first.

Locations (1)

St. Antonius ZiekenhuisNieuwegein, Utrecht, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT06861387