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Study identifier: NCT06859892 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Dexmedetomidine-Esketamine Combination and Sleep Disturbances After Major Noncardiac Surgery

Condition: Adults · Major Noncardiac Surgery · Dexmedetomidine  ·  Sponsor: Peking University First Hospital

PhasePhase 4
Planned participants476
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Sleep disturbances are common early after major surgery, and are associated with delayed recovery. A previous study showed that dexmedetomidine-esketamine combination as a supplement to patient-controlled intravenous analgesia improved postoperative analgesia and subjective sleep quality in patients after scoliosis correction surgery. The purpose of this trial is to test the hypothesis that dexmedetomidine-esketamine combination used as a supplement during general anesthesia and postoperative intravenous analgesia may reduce sleep disturbances in adult after major noncardiac surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Mo Li, MD, PhD  ·  +86 19801260665  ·  2361011139@pku.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University First HospitalBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT06859892