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Study identifier: NCT06859255 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

In-vitro Benchmarking of Currently Available Heart Valve Prostheses for Surgical and Percutaneous Treatment of Aortic Stenosis With Small Annulus, Followed by In-vivo Validation

Condition: Severe Aortic Valve Stenosis  ·  Sponsor: IRCCS Policlinico S. Donato

PhaseNA
Planned participants200
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNo

About this study

The general objective of this study is to compare in vitro and in vivo the hemodynamic performance of different types of aortic valve prostheses and possible surgical implantation techniques. The study involves the collection of data deriving from tests and procedures foreseen by normal clinical practice, including a transthoracic color Doppler echocardiogram, to which is added a 4DFlow cardiac MRI (magnetic resonance imaging) without contrast medium, to be performed between 1 and 3 months after the operation. The study will last 24 months and the patients involvement will end approximately 1-3 months after the intervention. There are no direct benefits expected from participation in the study. However, the instrumental data obtained by echocardiogram and Magnetic Resonance Imaging will be useful for monitoring the medium-term surgical outcome of patients after surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Agnese Rossi, Study Coordinator  ·  00393409009040  ·  agnese.rossi@grupposandonato.it

Giacomo Bortolussi, Researcher - Cardiac Surgeon  ·  003900393246943755  ·  giacomo.bortolussi@grupposandonato.it

Always discuss trial participation with your own doctor first.

Locations (2)

Policlinico di BariBari, Apulia, ItalyRecruiting
IRCCS Policlinico San DonatoSan Donato, Lombardy, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT06859255